Most people get some GI upset, especially while titrating up. Here's the full list — common and serious — plus the boxed warning worth actually reading.
Most side effects are GI — nausea, diarrhea, decreased appetite, vomiting, constipation, indigestion, stomach pain. Worst right after a dose increase, easing at a stable dose.
Per Mounjaro (tirzepatide) prescribing information, Eli Lilly. Not medical advice — call your prescriber about any symptom that worries you.
The most reported side effect. Slowed stomach emptying is the mechanism, not a sign anything's wrong.
Either direction is common, especially early on and after a dose increase.
Part of how the drug works — but rapid, unintentional weight loss is worth flagging to your prescriber.
Less common than nausea but listed. Persistent vomiting is a reason to call your prescriber.
Mild abdominal discomfort is common; severe pain that won't go away is not — see below.
Redness or soreness where you inject. Rotating sites reduces this.
Mounjaro carries a boxed warning: tirzepatide caused thyroid C-cell tumors in rodent studies, and it's not known if this occurs in people. Do not use Mounjaro if you or a family member has had medullary thyroid carcinoma (MTC) or have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). This list is not exhaustive — read the full prescribing information and ask your prescriber about anything unclear.
Tag nausea, appetite changes, or anything else against the exact dose and day it happened.
See whether symptoms cluster around dose increases — useful context for your next appointment.
A clean timeline of dose, site, and symptoms — ready to share, no digging through notes.
Never lose track of which dose you're on — the app carries your titration schedule automatically.
Cuts down on injection-site soreness by suggesting where to go next.
Every injection, dose and note on one synced timeline across devices.
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